THE ENZYMATIC RING EXPANSION OF PENICILLINS TO CEPHALOSPORINS: SIDE CHAIN SPECIFICITY

DOI: 10.1016/S0040-4020(01)86840-X

Source and publish data:

Tetrahedron p. 3009 - 3014 (1987)

Update date:2022-08-04

Topics:

Authors:

Baldwin, Jack E.

Adlington, Robert M.

Crabbe, M. James

Knight, Graham

Nomoto, Takashi

et al. et al.

Read Full Text PDF DownLoad Join now for total 90,000,000 free articles

Article abstract of DOI:10.1016/S0040-4020(01)86840-X

Structural variants of the acylamino side chain of penicillins have been tested as substrates for Deacetoxy/Deacetyl Cephalosporin C Synthetase from C. acremonium CO 728.A six carbon chain terminating in a carboxyl group was found to permit efficient ring expansion to cephems, with the exception of δ-(L-α-aminoadipoyl).

Full text of DOI:10.1016/S0040-4020(01)86840-X

Products guided by the article

Product name:(2S,5R,6R)-1-aza-3,3'-dimethyl-6-(5-p-nitrobenzyloxycarbonylpentanamido)-7-oxo-4-thiabicyclo<3.2.0>heptane-2-carboxylic acid p-nitrobenzyl ester

Cas No:112078-58-7

R&D Labs maybe for 112078-58-7

Chengdu Green technology Co.,Ltd.

Contact:86-28-82608355

Address:C9 ,Economic Headquarters, Economic Development Zone, Chengdu.
Win-Win chemical Co.Ltd

website:http://www.win-winchemical.com

Contact:0086-577-64498589

Address:6F, No. 396 Xingping Road, Longwan Industrial Zone, Wenzhou City, Zhejiang, 325000 P.R.China
shanghai jinshan pharmaceutical Co.,Ltd

Contact:021-57363011，13681638167

Address:No. 7966 Tingfeng Road,Jinshan,Shanghai,China
Nanjing Ruizhi Industry & Technologh Co.，Ltd.

Contact:+86-25-86808110

Address:441-4-A5,NO.12 Longzang Avenue,Yuhuatai District,210039,Nanjing
Zhejiang Chemline International Co., Ltd.

Contact:+86-571-88062298

Address:Hengdian Industry Area, Dongyang, Zhejiang, China

Relevant to this article

Characteristic fluorescence behavior of dialkynylpyrene derivatives in hydrophobic cavity of protein

Doi:10.1246/cl.2009.84
(2009)
Enzymatic synthesis of peptides on a solid support

Doi:10.1039/b816847d
(2009)
Substitution and isomerization of asymmetric β-diketonato rhodium(I) complexes: A crystallographic and computational study

Doi:10.1021/om1000138
(2010)
Synthesis of diphenyl(nitroaryl)phosphine oxides via oxidative nucleophilic substitution of hydrogen in nitroarenes with diphenylphosphine anion

Doi:10.1055/s-0028-1087354
(2008)
Five-membered 2,3-dioxoheterocycles: LVIII. Reaction of methyl 1-aryl-3-aroyl-4,5-dioxo-4,5-dihydro-1H-pyrrol-2-carboxylates with substituted 1-methyl-3,4-dihydroisoquinolines. New approach to the synthesis of steroid 13-azaanalogs

Doi:10.1134/S1070428008050102
(2008)
Stereoselective synthesis of β-hydroxy-α-methylcarboxylic acid thiol esters via vinyloxyboranes

Doi:10.1016/S0040-4039(01)93682-2
(1979)

Article Doi