Highly diastereoselective dielsalder reaction mediated by a chiral auxiliary derived from amino indanol: The role of conformation on diastereoselectivity

Article abstract of DOI:10.1016/0040-4039(95)01584-5

The oxazolidinone 2 derived from amino indanol 1 functions as a very efficient chiral auxiliary for the Diels-Alder reaction. The effect of conformation has been explored using a range of constrained phenyl glycinol analogues.