SYNTHESIS OF 2-VINYL-1,3-DIOLS VIA HIGHLY STEREOSELECTIVE REDUCTION OF 2-VINYL ALDOLS USING TRIMETHYLSILYL STEREO-DIRECTING GROUP

DOI: 10.1016/S0040-4039(00)85440-4

Source and publish data:

Tetrahedron Letters p. 6233 - 6236 (1986)

Update date:2022-08-04

Topics:

Authors:

Suzuki, Keisuke

Shimazaki, Masato

Tsuchihashi, Gen-ichi

Read Full Text PDF DownLoad Join now for total 90,000,000 free articles

Article abstract of DOI:10.1016/S0040-4039(00)85440-4

Stereo-defined 2-vinyl-1,3-diols are synthesized by the reduction of aldol derivatives bearing α-trimethylsilylvinyl group at C(2) (LiBEt3H/THF, -78 deg C), which proceeds highly stereoselectively to give 1,2-syn isomer as the sole product.

Full text of DOI:10.1016/S0040-4039(00)85440-4

Products guided by the article

Product name:(2R,3R,4S)-1-Benzyloxy-3-(1-trimethylsilanyl-vinyl)-dodecane-2,4-diol

Cas No:112318-45-3

R&D Labs maybe for 112318-45-3

Wuxi Forest Biological Co.,Ltd

Contact:+86-510-81602300

Address:Room 317,Building D, No.159 middle Chengjiang Road,Jiangyin Wuxi city.
Taizhou Elitechemie MediPharma Technology Co.,Ltd.

Contact:+86-523-86810021

Address:Building G14,NO.1 Avenue,China Medical City, Taizhou, Jiangsu,China
Sichuan Sangao Biochemical Co., Ltd

Contact:+86-28-84874233

Address:19F, Bldg.2, Shudu Center, Tianfu 2nd St., Hi-tech zone, Chengdu 610041, Sichuan Province, China.
Nanjing Spring & Autumn Biological Engineering Co., Ltd.

Contact:86-180510-83338

Address:Suite# 210, No. 1 BuildingNanjing Agricultural Biotechnology High-tech Entrepreneurship Center, No. 4 Tongwei Road, Xuanwu District, Nanjing,China
TAIXING BEST NEW MATERIALS CO., LTD

Contact:0523-87998158;

Address:No.18 Zhonggang Road，Taixing City ，Jiangsu , China

Relevant to this article

Photoinduced intramolecular macrocyclization reaction between a Bpa and a met residue in a helical peptide: 3D structures of the diastereomeric products

Doi:10.1002/chem.200802066
(2009)
A Stereoselective Approach to Annulated Tetrahydrofurans by Iodocyclisations of 2-Alkenylcycloalkan-1-ols

Doi:10.1039/c39940000719
(1994)
Microbial Resolution and Asymmetric Oxidation Related to Optically Active 1,2-Bis(methoxyphenyl)ethane-1,2-diol

Doi:10.1039/c39890000754
(1989)
Doi:10.1139/v60-160
(1960)
Reaction of 4-acylaminomethylpyridine N-oxides with phenylbutazone in the presence of acetic anhydride

Doi:10.1002/jhet.5570240339
(1987)
A New Synthetic Method for the Preparation of Ketones by Denitration of α-Nitro Ketones

Doi:10.1055/s-1987-27995
(1987)

Article Doi