SYNTHESIS OF THE OPTICALLY ACTIVE 4-O-PHOSPHONO-D-GLUCOSAMINE DERIVATIVES RELATED TO THE NONREDUCING-SUGAR SUBUNIT OF BACTERIAL LIPID A

Article abstract of DOI:10.1016/0008-6215(87)80207-0

The optically active lipid A-subunit homologs named GLA-46, GLA-47, GLA-59, and GLA-60 have been synthesized stepwise by successive acylation at N-2 and O-3 of benzyl 2-amino-2-deoxy-4,6-O-isopropylidene-β-D-glucopyranoside with the 3-O-(benzyloxy)methyl