Reactions of Allenylic Tin Reagents to N-Alkoxycarbonyl-isoquinolinium and -quinolinium Salts. Effective Introduction of 2-Alkynylic Groups to Isoquinoline and Quinoline Systems

Article abstract of DOI:10.1246/cl.1987.1519

Reaction of allenylic tin reagents with isoquinoline in the presence of chloroformate esters as acylating agents give 2-alkoxycarbonyl-1-(2-alkynyl)-1,2-dihydroisoquinolines in good to excellent yields.Similarly, the reactions with quinoline give 1- alkoxycarbonyl-2-(2-alkynyl)-1,2-dihydroquinolines exclusively.