
Russian Journal of Bioorganic Chemistry p. 752 - 758 (2009)
Update date:2022-07-30
Topics:
Formanovsky
Popova
Mikhura
The total large-scale synthesis of a natural toxin argiopine, a polymethylenepolyamine derivative, was developed. It consisted of 26 stages and included three key block schemes. Most of the stages proceeded quantitatively, which excluded the necessity of using the chromatographic separation of intermediates.
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