Catalytic and stoichiometric synthesis of novel 3-aminocarbonyl-, 3-alkoxycarbonyl-, and 3-amino-4-indolylmaleimides

Article abstract of DOI:10.1002/ejoc.200800964

Novel nonsymmetrically substituted 4-indolylmaleimides have been synthesized via palladium-catalyzed alkoxy- and aminocarbonylation of 3-bromo-1-methyl-4-(2-methyl-3-indolyl) maleimide (1) with alcohols and amines in the presence of carbon monoxide. The r