Journal of the Chemical Society. Chemical communications p. 829 - 831 (1983)
Update date:2022-07-30
Topics: Synthesis Chiral Lactone Derivative Disubstituted
Baker, Raymond
Boyes, R. Hugh O.
Broom, D. Mark P.
Devlin, J. Alastair
Swain, Christopher J.
A synthesis of two diprotected (4S,6S)-4-hydroxy-6-hydroxymethyltetrahydropyran-2-ones has been developed from laevoglucosan; reaction of these lactones with a substituted lithium acetylide derivative followed by hydrogenation and acid catalysed cyclisati
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