Terminal Bifunctional Retinoids. Synthesis and Evaluation Related to Cancer Chemopreventive Activity

DOI: 10.1021/jm00401a011

Source and publish data:

Journal of Medicinal Chemistry p. 1124 - 1130 (1988)

Update date:2022-08-03

Topics:

Authors:

Shealy, Y. Fulmer

Krauth, Charles A.

Riordan, James M.

Sani, Brahma P.

Read Full Text PDF DownLoad Join now for total 90,000,000 free articles

Article abstract of DOI:10.1021/jm00401a011

Retinoids that have two functional groups at the side-chain terminus have been synthesized.The two terminal functional groups are combinations of the carboxyl, carbethoxy, and N-(ethylamino)carbonyl groups.The synthesis route is based on the sodium amide

Full text of DOI:10.1021/jm00401a011

Products guided by the article

Product name:ethyl 14-<(ethylamino)carbonyl>retinoate

Cas No:113089-11-5

R&D Labs maybe for 113089-11-5

Meryer (Shanghai) Chemical Technology Co., Ltd.

website:http://www.meryer.com/cn/index/

Contact:+86-755-86170518

Address:Minhang,Shanghai, China
Landz International Company Ltd.

Contact:0086-21-58891610

Address:985 Dongfang Road, Pudong, Shanghai 200122 China
Suzhou CarbonWell Pharma-Tech Co., Ltd

Contact:Tel: + 86 (0)512-8898-1216; + 86-18606258602

Address:2358 Changan Road, Wujiang Scientific Innovation Park, Wujiang, Jiangsu Province, P. R. China 215200
Nanjing Yuance Industry&Trade Co., Ltd.

website:http://www.njyuance.cn/

Contact:+86-25-85439097

Address:B1702, Aoti Bldg, No. 130, Aoti Avenue, Nanjing, China
Zhenjiang Haitong Chemical Industry Co., Ltd.

Contact:+86 (511) 8448-0369

Address:Baoyan Town, Dantu District, Zhenjiang City, Jiangsu, China

Relevant to this article

Design, synthesis, X-ray crystallographic analysis, and biological evaluation of thiazole derivatives as potent and selective inhibitors of human dihydroorotate dehydrogenase

Doi:10.1021/jm501127s
(2015)
THE SYNTHESIS OF SOME η⁶-KETOARENE-η⁵-CYCLOPENTADIENYLIRON CATIONS AND THEIR REDUCTION WITH SODIUM BOROHYDRIDE

Doi:10.1016/S0022-328X(00)98831-4
(1983)
Synthesis and biological activity of a new class of cytotoxic agents: N-(3-oxoprop-1-enyl)-substituted pyrimidines and purines

Doi:10.1021/jm00374a004
(1984)
Synthesis, characterization and optical properties of π-conjugated systems incorporating closo-dodecaborate clusters: New potential candidates for two-photon absorption processes

Doi:10.1039/b504414f
(2005)
Development of novel brush-type chiral stationary phases based on terpenoid selectors: HPLC evaluation and theoretical investigation of enantioselective binding interactions

Doi:10.1016/j.tetasy.2006.11.036
(2006)
Electron-rich piano-stool iron σ-acetylides. Electronic structures of arylalkynyl iron(III) radical cations

Doi:10.1021/om0505108
(2005)

Article Doi