Terminal Bifunctional Retinoids. Synthesis and Evaluation Related to Cancer Chemopreventive Activity

DOI: 10.1021/jm00401a011

Source and publish data:

Journal of Medicinal Chemistry p. 1124 - 1130 (1988)

Update date:2022-08-03

Topics:

Authors:

Shealy, Y. Fulmer

Krauth, Charles A.

Riordan, James M.

Sani, Brahma P.

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Article abstract of DOI:10.1021/jm00401a011

Retinoids that have two functional groups at the side-chain terminus have been synthesized.The two terminal functional groups are combinations of the carboxyl, carbethoxy, and N-(ethylamino)carbonyl groups.The synthesis route is based on the sodium amide

Full text of DOI:10.1021/jm00401a011

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Product name:ethyl 14-<(ethylamino)carbonyl>retinoate

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