Antihypertensive thiadiazoles. 2. Vasodilator activity of some 2-aryl-5-guanidino-1,3,4-thiadiazoles

DOI: 10.1021/jm00400a004

Source and publish data:

Journal of Medicinal Chemistry p. 906 - 913 (1988)

Update date:2022-08-04

Topics:

Authors:

Turner Turner

Myers Myers

Gadie Gadie

Hale Hale

Horsley Horsley

Nelson Nelson

Pape Pape

Saville Saville

Doxey Doxey

Berridge

Read Full Text PDF DownLoad Join now for total 90,000,000 free articles

Article abstract of DOI:10.1021/jm00400a004

Some 2-aryl-5-guanidino-(or N-substituted guanidino)-1,3,4-thiadiazoles and closely related analogues were found to lower blood pressure in metacorticoid (DOCA) hypertensive rats. In the unsubstituted guanidines that exhibited low toxicity, optimum activi

Full text of DOI:10.1021/jm00400a004

Products guided by the article

Product name:Carbamodithioic acid, [5-(2-methylphenyl)-1,3,4-thiadiazol-2-yl]-, methyl ester

Cas No:113113-54-5

R&D Labs maybe for 113113-54-5

Zibo Ocean International Trade Co.,Ltd(expird)

Contact:+86 533 5160706

Address:1117, Hongtai Bld., Songling rd, Zichuan,Zibo,Shandong,China
Phantom-pharma

Contact:

Address:
Shenyang Mole pharmaceutical Technology Development Co.,Ltd

Contact:+86-24-31204918/13889278616

Address:No.44, wanliutang road, shenhe District of Shenyang
Xi'an Costrong Pharmaceutical Co., Ltd.

Contact:029- 68576496

Address:Room 2004,Shuibao Building,No.190,South Erhuan Rd, Yanta District,Xi'an,Shaan Xi,China
Hebei Lead Bio-Chemicals Co., Ltd.

website:http://www.ldbiochem.com

Contact:+86-311-87826503

Address:481, Heping West Road, Shijiazhuang,China

Relevant to this article

Enantioselective Synthesis of Trisubstituted Allenes via Cu(I)-Catalyzed Coupling of Diazoalkanes with Terminal Alkynes

Doi:10.1021/jacs.6b09674
(2016)
Facile iodine(III)-mediated approach for the regioselective chlorination of 2-aryl-2,3-dihydro-4(1H)-quinolones

Doi:10.1080/00397910802413865
(2009)
SYNTHESIS AND BIOLOGICAL ACTIVITY OF BIS-THIOSEMICARBAZONES OF 3-ETHOXY-2-OXOBUTYRALDEHYDE AND THEIR COMPLEXES WITH Cu(II)

Doi:10.1007/BF00769807
(1984)
Facile and efficient synthesis of novel oxazine, oxazepine and phenoxazine of chromenones fused with 1,4-naphthoquinone

Doi:10.3987/COM-08-S(F)30
(2009)
A general, convenient and highly efficient synthesis of diarylmethanes by copper-catalyzed reaction

Doi:10.1016/0040-4039(96)00176-1
(1996)
Recycling the tert-butanesulfinyl group in the synthesis of amines using tert-butanesulfinamide

Doi:10.1021/jo9001883
(2009)

Article Doi