SYNTHESIS OF MACROCYCLIC TERPENOIDS BY INTRAMOLECULAR CYCLIZATION IX. TOTAL SYNTHESIS OF (+/-)-OBSCURONATIN AND (+)-BIFLORA-4,10(19),15-TRIENE.

Article abstract of DOI:10.1016/S0040-4039(01)81685-3

Stereoselective total synthesis of (+/-)-obscuronatin, a marine diterpene with a 10-membered ring, has been achieved utilizing the anion-induced cyclization of an acyclic epoxy sulfide.The synthesis confirmed the stereostructure of the natural product.