Asymmetric Electrophilic Substitution on Phenols. 2. Enantio- and Diastereoselective Synthesis of o-Hydroxyatrolactic Esters

DOI: 10.1021/jo00243a033

Source and publish data:

Journal of Organic Chemistry p. 1779 - 1785 (1988)

Update date:2022-08-03

Topics:

Authors:

Casiraghi, Giovanni

Bigi, Franca

Casnati, Giuseppe

Sartori, Giovanni

Soncini, Paolo

et al. et al.

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Article abstract of DOI:10.1021/jo00243a033

Both 2R and 2S stereoisomers of o-hydroxyatrolactic acid esters 3-5 are available with respective absolute configuration from phenols 1 and pyruvic acid esters 2 by using menthol only as a chiral inductor.Three asymmetric approaches were designed based on

Full text of DOI:10.1021/jo00243a033

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