Asymmetric Electrophilic Substitution on Phenols. 2. Enantio- and Diastereoselective Synthesis of o-Hydroxyatrolactic Esters

DOI: 10.1021/jo00243a033

Source and publish data:

Journal of Organic Chemistry p. 1779 - 1785 (1988)

Update date:2022-08-03

Topics:

Authors:

Casiraghi, Giovanni

Bigi, Franca

Casnati, Giuseppe

Sartori, Giovanni

Soncini, Paolo

et al. et al.

Read Full Text PDF DownLoad Join now for total 90,000,000 free articles

Article abstract of DOI:10.1021/jo00243a033

Both 2R and 2S stereoisomers of o-hydroxyatrolactic acid esters 3-5 are available with respective absolute configuration from phenols 1 and pyruvic acid esters 2 by using menthol only as a chiral inductor.Three asymmetric approaches were designed based on

Full text of DOI:10.1021/jo00243a033

Products guided by the article

Product name:(R)-2-Hydroxy-2-(2-hydroxy-phenyl)-propionic acid (1R,2S,5R)-2-isopropyl-5-methyl-cyclohexyl ester

Cas No:113322-85-3

R&D Labs maybe for 113322-85-3

Synchem Pharma Co.,Ltd(expird)

Contact:+0086-21-61984905-1

Address:Building 60,Zimian Park, LongYang industrial Area, 1515Nong，Yuandong Road Fengxian District, Shanghai ,China
Changzhou Anyi Biochem Co., Ltd.(expird)

Contact:+86-519-88836158

Address:no,51 caoda
Xi'an Kaixiang Photoelectric Technology Co., Ltd

website:http://www.kxmaterials.com/

Contact:86-29-15991651477

Address:Building 6, Biopharmaceutical Industry R&D Cluster Base, No. 16, Caotang 4th Road, Caotang Science and Technology Industrial Base, High-tech Zone, Xi'an City, Shaanxi Province, China
Hebei Fulong Import & Export Co., Ltd.

Contact:86-311-87795661

Address:15A19 Zhongyuan Building,368 Youyi North Street,Shijiazhuang 050070,China
Shanghai PuYi Chem-Tech Co.,Ltd.

Contact:+86-21-57687505-227

Address:3 Floor, Building 11, No 201 MinYi Road, Songjiang District, Shanghai 201612, China

Relevant to this article

Photocatalytic Oxidative [2+2] Cycloelimination Reactions with Flavinium Salts: Mechanistic Study and Influence of the Catalyst Structure

Doi:10.1002/cplu.202000767
(2021)
Study of electronic effect in bifunctional catalysts for the copolymerization of CO₂ and PO/CHO

Doi:10.1002/jccs.202000103
(2020)
PhI(OAc)₂-promoted umpolung acetoxylation of enamides for the synthesis of α-acetoxy ketones

Doi:10.1007/s11426-016-0478-3
(2017)
Synthesis and biological activity of certain derivatives of anesthesine (Benzocaine)

Doi:10.1134/S1070363208060261
(2008)
Synthesis of mycobacterial triacylated phosphatidylinositol dimannoside containing an acyl lipid chain at 3-O of inositol

Doi:10.1021/ol1008137
(2010)
Asymmetric dihydroxylation of acrolein acetals: Synthesis of stable equivalents of Enantiopure glyceraldehyde and glycidaldehyde

Doi:10.1016/0040-4039(92)88149-Y
(1992)

Article Doi