Synthesis of Masked Glyoxal Monoxime and 1-Hydroxylaminoacetaldehyde Derivatives

Article abstract of DOI:10.1055/s-1987-28029

Sodium ethoxide-catalyzed cleavage of azo-N,N'-bis(2,2-diethoxyethyl)-N,N'-dioxide (2) to an E/Z mixture (6.5:1) of 1-hydroxyimino-2,2-diethoxyethane (3a) is reported.Alkylation of the oxime sodium salt provides mainly the E-isomers of the alkyloxyimino-2