Function of the amino sugar and N-terminal amino acid of the antibiotic vancomycin in its complexation with cell wall peptides

Article abstract of DOI:10.1021/ja00217a042

Four N-acetylated derivatives of vancomycin (1) were prepared: the derivative at the N-terminus (2, NAcV), the N-acetyl derivative on the vancosamine residue (3, N'AcV), the N,N'-bis derivative (4, DiAcV), and the N-terminal derivative of the aglycon (6,