6-(Alkylamino)-3-aryl-1,2,4-triazolophthalazines. A New Class of Benzodiazepine Receptor Ligands

DOI: 10.1021/jm00401a010

Source and publish data:

Journal of Medicinal Chemistry p. 1115 - 1123 (1988)

Update date:2022-09-26

Topics:

Authors:

Tarzia, Giorgio

Occelli, Emilio

Toja, Emilio

Barone, Domenico

Corsico, Nerina

et al. et al.

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Article abstract of DOI:10.1021/jm00401a010

Some 6-(alkylamino)-3-aryl-1,2,4-triazolo<3,4-a>phthalazines have been shown to displace diazepam from rat brain specific binding sites, in vitro, with K_i (nM) values comparable to those of reference benzodiazepines and to have anticonvulsant (

Full text of DOI:10.1021/jm00401a010

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