A STEREOCONTROLLED SYNTHESIS OF 3-(1'-HYDROXYETHYL)-2-AZETIDINONES THROUGH TRIMETHYLSILYL TRIFLUOROMETHANESULPHONATE CATALYZED CONDENSATION OF SILYL KETENE ACETAL DERIVED FROM ETHYL 3-HYDROXYBUTYRATE AND IMINE

DOI: 10.1016/S0040-4039(00)96502-X

Source and publish data:

Tetrahedron Letters p. 4335 - 4338 (1987)

Update date:2022-07-29

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Authors:

Guanti, Giuseppe

Narisano, Enrica

Banfi, Luca

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Article abstract of DOI:10.1016/S0040-4039(00)96502-X

The silyl ketene acetal 2, prepared from ethyl 3-hydroxybutyrate, reacted with benzylidene aniline in the presence of trimethylsilyl trifluoromethanesulphonate to furnish in satisfactory yield the β-amino ester 3 as a single diastereomer, which was subseq

Full text of DOI:10.1016/S0040-4039(00)96502-X

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