Journal of Medicinal Chemistry p. 1141 - 1147 (1988)
Update date:2022-08-04
Topics: Enzyme Active site Thymidylate Synthase
Chang
Schwepler
Decedue
Balzarini
De Clercq
Mertes
The requirements for active-site binding of thymidylate synthase from three sources, Lactobacillus casei, murine leukemia L1210, and human lymphoblast (Molt/4F), were investigated by analyzing the binding of a series of 5-(p-substituted phenyl)-2'-deoxyur
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