Design, synthesis, and evaluation of novel fluoroquinolone - Aminoglycoside hybrid antibiotics

DOI: 10.1021/jm900028n

Source and publish data:

Journal of Medicinal Chemistry p. 2243 - 2254 (2009)

Update date:2022-08-05

Topics:

Authors:

Pokrovskaya, Varvara

Belakhov, Valery

Hainrichson, Mariana

Yaron, Sima

Baasov, Timor

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Article abstract of DOI:10.1021/jm900028n

A series of new hybrid structures containing fluoroquinolone (ciprofloxacin) and aminoglycoside (neomycin) antibiotics linked via 1,2,3-triazole moiety were designed and synthesized, and their antibacterial activities were determined against both Gram-neg

Full text of DOI:10.1021/jm900028n

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