The influence of an ethylene spacer on the 5-HT1A and 5-HT2A receptor affinity of arylpiperazine derivatives of amides with N-acylated amino acids and 3-differently substituted pyrrolidine-2,5-diones

DOI: 10.1016/j.ejmech.2008.05.021

Source and publish data:

European Journal of Medicinal Chemistry p. 800 - 808 (2009)

Update date:2022-08-04

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Authors:

Zajdel, Pawel

Subra, Gilles

Verdie, Pascal

Bojarski, Andrzej J.

Duszynska, Beata

Basista, Katarzyna

Obniska, Jolanta

Martinez, Jean

Pawlowski, Maciej

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Article abstract of DOI:10.1016/j.ejmech.2008.05.021

A library of ethylene analogs of the previously described arylpiperazines with N-acylated amino acids was synthesized on SynPhase Lanterns and the library representatives were evaluated for their 5-HT_1A and 5-HT_2A receptor affinities

Full text of DOI:10.1016/j.ejmech.2008.05.021

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