2-(2-Aryl-2-oxoethylidene)-1,2,3,4-tetrahydropyridines. Novel isomers of 1,4-dihydropyridine calcium channel blockers

DOI: 10.1021/jm00403a030

Source and publish data:

Journal of Medicinal Chemistry p. 1659 - 1664 (1988)

Update date:2022-08-05

Topics:

Authors:

Taylor Taylor

Badger Badger

Steffen Steffen

Haleen Haleen

Pugsley Pugsley

Shih Shih

Weishaar

Read Full Text PDF DownLoad Join now for total 90,000,000 free articles

Article abstract of DOI:10.1021/jm00403a030

The title compounds are novel double bond isomers of 1,4-dihydropyridine-type calcium channel blockers (CCB). These derivatives were prepared by using the Hantzsch dihydropyridine synthesis. The assignment of structure was based on spectroscopic data and

Full text of DOI:10.1021/jm00403a030

Products guided by the article

Product name:(3S,4S)-4-(2,3-Dichloro-phenyl)-6-methyl-2-[2-oxo-2-phenyl-eth-(Z)-ylidene]-1,2,3,4-tetrahydro-pyridine-3,5-dicarboxylic acid diethyl ester

Cas No:114957-71-0

R&D Labs maybe for 114957-71-0

Tai zhou world Pharm & Chem Co., Ltd

Contact:+86-576-85301198

Address:Rome 1001,wangjiang plaza,unti 2,jinshan east Road linhai,zhejiang,china
Shijiazhuang Haitian Amino Acid Co., Ltd.

Contact:+86-311-88908111

Address:Shijiazhuang Hebei province,China
Zhejiang Newfine Industry Co.,Ltd.

Contact:+86-573-82262042

Address:No.225,Dongqing Road, garoms@163.com
NingBO Hong Xiang Biochem.Co.Ltd

website:http://www.hxbiochem.com

Contact:0574-66003444

Address:Ning Bo Bei Lun
Beijing Apis Biotechnology Co., Ltd.

Contact:86-010-67856775-8551

Address:NO.4PUHUANGYU ROAD,FENTAI DISTRICT, BEIJING, CHINA

Relevant to this article

Doi:10.1021/ja00225a038
(1988)
Radical additions to allyl bromides. A synthetically useful, 'Tin-Free' method for carbon-carbon bond formation

Doi:10.1016/j.tetlet.2009.02.154
(2009)
A new and rapid N-alkylation of 3,6-epoxy-hexahydrophthalimides

Doi:10.1081/SCC-120002121
(2002)
Synthesis of 2-(5-((5-(4-chlorophenyl)furan-2-yl)methylene)-4-oxo-2-thioxothiazolidin-3-yl)acetic acid derivatives and evaluation of their cytotoxicity and induction of apoptosis in human leukemia cells

Doi:10.1016/j.bmc.2009.01.016
(2009)
Synthesis and in vitro antimicrobial screening of new pyrano[4,3-b]pyrane derivatives of 1H-pyrazole

Doi:10.1016/j.cclet.2011.09.012
(2012)
Visible light-induced transformation of aldehydes to esters, carboxylic anhydrides and amides

Doi:10.1039/c9nj01984g
(2019)

Article Doi