2-(2-Aryl-2-oxoethylidene)-1,2,3,4-tetrahydropyridines. Novel isomers of 1,4-dihydropyridine calcium channel blockers

DOI: 10.1021/jm00403a030

Source and publish data:

Journal of Medicinal Chemistry p. 1659 - 1664 (1988)

Update date:2022-08-05

Topics:

Authors:

Taylor Taylor

Badger Badger

Steffen Steffen

Haleen Haleen

Pugsley Pugsley

Shih Shih

Weishaar

Read Full Text PDF DownLoad Join now for total 90,000,000 free articles

Article abstract of DOI:10.1021/jm00403a030

The title compounds are novel double bond isomers of 1,4-dihydropyridine-type calcium channel blockers (CCB). These derivatives were prepared by using the Hantzsch dihydropyridine synthesis. The assignment of structure was based on spectroscopic data and

Full text of DOI:10.1021/jm00403a030

Products guided by the article

Product name:(3S,4S)-4-(2,3-Dichloro-phenyl)-6-methyl-2-[2-oxo-2-phenyl-eth-(Z)-ylidene]-1,2,3,4-tetrahydro-pyridine-3,5-dicarboxylic acid diethyl ester

Cas No:114957-71-0

R&D Labs maybe for 114957-71-0

Tianjin Anda North Industrial & Business Co.Ltd.

Contact:86-22-24999306

Address:No.11 Erwei Road,Dongli Development Area,Tianjin,China
SHANXI XINTIANYUAN PHARMACEUTICAL CO., LTD.

website:http://www.tychemical.com

Contact:0086-358-3521713 3521715

Address:No. 1 Yintong Road, Shanxi Jiaocheng Economic Development Zone, Xiajiaying Town, Jiaocheng County, Lvliang City, Shanxi Province, China
Afine Chemicals Limited

website:http://www.afinechem.com

Contact:+86-571-85134551

Address:No. 206 Zhen Hua Road, Hangzhou 310030, Zhejiang, China
Wuxi Pharma-Trading Import & Export Co.,Ltd.

Contact:+86-510-82304590 82716390

Address:Room 523,Youzu Alliance Building,No.88 Renmin Zhonglu,Wuxi,Jiangsu,China
NINGBO PANGS CHEM INT’L CO.,LTD.

Contact:+86-574-27666845

Address:FLOOR 21,BUILDING NO.11,XIN TIAN DI,NO.689 SHI JI ROAD,NINGBO CHINA

Relevant to this article

Doi:10.1021/ja00225a038
(1988)
Radical additions to allyl bromides. A synthetically useful, 'Tin-Free' method for carbon-carbon bond formation

Doi:10.1016/j.tetlet.2009.02.154
(2009)
A new and rapid N-alkylation of 3,6-epoxy-hexahydrophthalimides

Doi:10.1081/SCC-120002121
(2002)
Synthesis of 2-(5-((5-(4-chlorophenyl)furan-2-yl)methylene)-4-oxo-2-thioxothiazolidin-3-yl)acetic acid derivatives and evaluation of their cytotoxicity and induction of apoptosis in human leukemia cells

Doi:10.1016/j.bmc.2009.01.016
(2009)
Synthesis and in vitro antimicrobial screening of new pyrano[4,3-b]pyrane derivatives of 1H-pyrazole

Doi:10.1016/j.cclet.2011.09.012
(2012)
Visible light-induced transformation of aldehydes to esters, carboxylic anhydrides and amides

Doi:10.1039/c9nj01984g
(2019)

Article Doi