Enantioselective total synthesis of ingramycin

DOI: 10.1016/S0040-4020(01)90315-1

Source and publish data:

Tetrahedron p. 4395 - 4406 (1987)

Update date:2022-08-02

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Authors:

Tanner, David

Somfai, Peter

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Article abstract of DOI:10.1016/S0040-4020(01)90315-1

An enantioselective total synthesis of the 14-membered macrolide antibiotic ingramycin, 1, is described. In a convergent approach three chiral fragments A,B and C are assembled, the allylic bromide A deriving its chirality from L-serine while the asymmetr

Full text of DOI:10.1016/S0040-4020(01)90315-1

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