M3 muscarinic acetylcholine receptor antagonists: SAR and optimization of bi-aryl amines

DOI: 10.1016/j.bmcl.2009.01.098

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Bioorganic and Medicinal Chemistry Letters p. 1686 - 1690 (2009)

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Article abstract of DOI:10.1016/j.bmcl.2009.01.098

Exploration of multiple regions of a bi-aryl amine template led to the identification of highly potent M₃ muscarinic acetylcholine receptor antagonists such as 14 (pA₂ = 11.0) possessing good sub-type selectivity for M₃ ov

Full text of DOI:10.1016/j.bmcl.2009.01.098

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Article Doi

M3 muscarinic acetylcholine receptor antagonists: SAR and optimization of bi-aryl amines

DOI: 10.1016/j.bmcl.2009.01.098

Source and publish data:

Authors:

Article abstract of DOI:10.1016/j.bmcl.2009.01.098

Full text of DOI:10.1016/j.bmcl.2009.01.098

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