Novel modifications in the series of O-(2-phthalimidoethyl)-N-substituted thiocarbamates and their ring-opened congeners as non-nucleoside HIV-1 reverse transcriptase inhibitors

DOI: 10.1016/j.ejmech.2008.09.024

Source and publish data:

European Journal of Medicinal Chemistry p. 1650 - 1663 (2009)

Update date:2022-07-29

Topics:

Authors:

Spallarossa, Andrea

Cesarini, Sara

Ranise, Angelo

Bruno, Olga

Schenone, Silvia

La Colla, Paolo

Collu, Gabriella

Sanna, Giuseppina

Secci, Barbara

Loddo, Roberta

Read Full Text PDF DownLoad Join now for total 90,000,000 free articles

Article abstract of DOI:10.1016/j.ejmech.2008.09.024

The structure-activity relationships (SARs) of N-aryl-O-(2-phthalimidoethyl)thiocarbamates (C-TCs) and their imide ring-opened congeners (O-TCs) as non-nucleoside HIV-1 reverse transcriptase inhibitors were further investigated. The SAR strategy involved

Full text of DOI:10.1016/j.ejmech.2008.09.024

Products guided by the article

Product name:2-({[(1R)-2-({[(4-chlorophenyl)amino]carbonothioyl}oxy)-1-methylethyl]amino}carbonyl)benzoic acid

Cas No:1152595-82-8

R&D Labs maybe for 1152595-82-8

Xi'an Yuri Solar Co. Ltd

website:https://www.yurisolar.com/en

Contact:+86-29-81101199

Address:No. 560, East Hangtian Road, Xi'an, China
NEWSTAR CHEM ENTERPRISE LTD.

Contact:0572-2722882

Address:1201,F3,xinghuibandao,
Beijing Top Science biological technology co., LTD

Contact:+86-13439059536

Address:15-1705 jre three mile, Beijing 100000,CHINA
QINGDAO DEVELOP chemistry Co.,Limited

Contact:+86-532-85807910

Address:98#Nanjing Road, Qingdao, China 266071
Shanghai Gsyn Chemical Co.,Ltd.

Contact:86-021-67158290

Address:86-021-67158291

Relevant to this article

Low-coordinate organoyttrium complexes supported by β-diketiminato ligands

Doi:10.1021/om900082d
(2009)
Synthesis and biochemical evaluation of triazole/tetrazole-containing sulfonamides against thrombin and related serine proteases

Doi:10.1016/j.bmcl.2011.07.023
(2011)
Reactions of organoboranes with carbanions bearing three potential leaving groups: unusual processes, products and mechanisms

Doi:10.1016/j.tet.2016.09.005
(2016)
Indeno[1,2-b]indole derivatives as a novel class of potent human protein kinase CK2 inhibitors

Doi:10.1016/j.bmc.2012.02.017
(2012)
Lithium Enolate Additions to the Tropone Nucleus

Doi:10.1021/jo00254a040
(1988)
A white-light-emitting molecule: Frustrated energy transfer between constituent emitting centers

Doi:10.1021/ja902533f
(2009)

Article Doi