Preparation of New Nitrogen-Bridged Heterocycles. 16. Facile Synthesis of Thienoindolizine Derivatives

Article abstract of DOI:10.1246/bcsj.60.3713

2-Ethoxycarbonyl-3-methyl- and 3-phenylthieno<2,3-b>indolizine derivatives were first synthesized in moderate to good yields by the treatment of tricyclic 5,5a-dihydropyrido<2,1-c>thieno<3,2-e><1,4>thiazines with a dehydrogenating agent.In contrast to the cases of bicyclic 1,9a-dihydropyrido<2,1-c><1,4>thiazines, all of the thienonidolizines obtained here were rearranged products and desulfurized product could be obtained.