Synthesis and Characterization of Deoxy-3-O-methyl-5-C--α- and β-D-xylopyranoses. The First Sugar Analogue Having a Phosphinothioyl Group in the Hemiacetal Ring

Article abstract of DOI:10.1246/cl.1987.2081

Treatment of 5-deoxy-5-iodo-1,2-O-isopropylidene-3-O-methyl-α-D-xylofuranose with ethyl phenylphosphinothioate in the presence of sodium hydride, followed by the reduction with sodium dihydrobis-(2-methoxyethoxy)aluminate, and then with 0.5 M HCl-EtOH gav