A SHORT, ENANTIOSPECIFIC SHYNTHESIS OF THE 1α-HYDROXYVITAMIN D ENYNE A-RING SYNTHON

DOI: 10.1016/S0040-4039(00)96666-8

Source and publish data:

Tetrahedron Letters p. 4947 - 4950 (1987)

Update date:2022-07-29

Topics:

Authors:

Aurrecoechea, J. Miguel

Okamura, William H.

Read Full Text PDF DownLoad Join now for total 90,000,000 free articles

Article abstract of DOI:10.1016/S0040-4039(00)96666-8

The vitamin D A-ring synthon, the enyne 3b, was synthesized in 5 steps (37percent overall yield) from (S)-(+)-carvone (5).The key step was the SmI2-Pd⁰ mediated transformation of epoxypropargyl ester 6 to 3b.

Full text of DOI:10.1016/S0040-4039(00)96666-8

Products guided by the article

Product name:Acetic acid (1S,2R,4S,6S)-2-ethynyl-4-[1-methoxy-1-(4-nitro-benzoylperoxy)-ethyl]-1-methyl-7-oxa-bicyclo[4.1.0]hept-2-yl ester

Cas No:115540-13-1

R&D Labs maybe for 115540-13-1

Jiangsu King Road New Materials Co., Ltd.

website:http://www.jskingroad.com

Contact:0519-85720726 0519-85720721 15006126856

Address:No.1,Weihua Road,Xinbei District,Changzhou City,Jiangsu Province
Zhejiang Sucon Silicone Co.,Ltd

Contact:+86-575-88046692

Address:Qisheng Rd., Paojiang Industrial Zone, Shaoxing, Zhejiang, China.
Daicel Chiral Technologies (China)CO.,LTD

Contact:021-5046-0086*8

Address:Part C, FL 5, the 16th Building, No. 69, XiYa Road, WaiGaoQiao Free Trade Zone, Shanghai, 200131, P.R.China
Langchem

Contact:+86+21-58956006 15800617331

Address:402 Room, 150# Cailun Road, Zhangjiang high tech park, Shanghai
Hubei anhuang chemical Co.Ltd

Contact:

Address:308# dongwu avenue dongxihu district wuhan city

Relevant to this article

Experimental study on the reaction pathway of α-haloacetophenones with NaOMe: Examination of bifurcation mechanism

Doi:10.1246/bcsj.20130253
(2014)
Novel synthesis of 2,4-dihydro-5-amino[1,2,4]triazol-3-ones from 1,3-disubstituted thioureas

Doi:10.1055/s-0028-1087563
(2009)
SYNTHESE TOTALE DE DEUX ETHOXYCARBONYL-4 CEPHEMES FONCTIONNALISES OU NON EN POSITION 7 PAR UN GROUPEMENT PHTALIMIDO

Doi:10.1016/S0040-4020(01)85890-7
(1988)
Asymmetric synthesis of α,α-disubstituted α-amino acids via enantioselective alkylation of azlactones under biphasic conditions using P-spiro chiral tetraaminophosphonium salts as a phase-transfer catalyst

Doi:10.1055/s-0028-1087812
(2009)
Stereoselective synthesis of cis-β-methyl- and phenyl-substituted alkenylboronates by platinum-catalyzed dehydrogenative borylation

Doi:10.1002/anie.200805406
(2009)
Synthesis of a Trisaccharide Repeating Unit of the O-Antigen from Burkholderia multivorans and Its Oligomers

Doi:10.1002/ejoc.201500964
(2015)

Article Doi