8,2'-DIHYDROXYFLAVONE FROM PRIMULA PULVERULENTA

Article abstract of DOI:10.1016/0031-9422(88)80220-6

A novel flavone, isolated from the farinose exudate of Primula pulverulenta, was identified as 8,2'-dihydroxyflavone.This is the first naturally occurring flavone, in which ring A is oxygenated only at C-8.The structure was deduced from spectral comparisons with the structurally related flavones: 5,2'-, 3,2'- and 2',3'-dihydroxyflavone and confirmed by total synthesis.The spectral properties of other flavones oxygenation with a simple pattern are discussed in relation to 8,2'-dihydroxyflavone.Key Word Index - Primula pulverulenta; Primulaceae; farinose excretion; 8,2'-dihydroxyflavone; 8,2'-dimethoxyflavone.