Aromatase inhibitors: Synthesis, biological activity, and structure of 1,2-imidazolylmethylcyclopentanol derivatives

DOI: 10.1248/cpb.43.2152

Source and publish data:

Chemical and Pharmaceutical Bulletin p. 2152 - 2158 (1995)

Update date:2022-08-02

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Authors:

Kato Kato

Ikeda Ikeda

Sugita Sugita

Nitta Nitta

Enari Enari

Kashima Kashima

Konno Konno

Niimura Niimura

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Article abstract of DOI:10.1248/cpb.43.2152

Two series of 1,2-disubstituted imidazolylmethylcyclopentanol derivatives (5a-d, 10a-d) were prepared by using easily available methyl 2- oxocyclopentanecarboxylate as the starting material. Evaluation of the aromatase inhibitory activities in vitro was p

Full text of DOI:10.1248/cpb.43.2152

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