Molecules p. 2442 - 2461 (2008)
Update date:2022-07-30
Topics:
Sechi, Mario
Azzena, Ugo
Delussu, Maria Paola
Dallocchio, Roberto
Dessi, Alessandro
Cosseddu, Alessia
Pala, Nicolino
Neamati, Nouri
HIV-1 integrase (IN) is an attractive and validated target for the development of novel therapeutics against AIDS. In the search for new IN inhibitors, we designed and synthesized three series of bis-amide and hydrazide-containing derivatives of malonic acid. We performed a docking study to investigate the potential interactions of the title compounds with essential amino acids on the IN active site.
View MoreJinan Hongfangde Pharmatech Co.LTD
Contact:0531-88870908
Address:F Bldg,750#,Shunhua Rd,New&High-tech Zone,Jinan,Shandong,China 250101
Zhejiang kehong chemical co., ltd
Contact:0086-575-85522000
Address:xiner center RD binhai industrial zone shaoxing zhejiang province P.R.China,312073
QINGDAO ON-BILLION INDUSTRAIL CO.,LTD
website:http://www.obn.com.cn
Contact:+86-15005320811 +86-532-80681989
Address:F35 Parkson Mansion No.44-60 Zhongshan Rd.
Yingkou Sanzheng Organic Chemical Co. Ltd.
Contact:+86-417-3638818
Address:25 Gengxinli Village, Daqing Road, Yingkou, Liaoning, China
Shandong Hongxiang Zinc Co., Ltd
Contact:086-0311-66187879
Address:DaWang developing zone
Doi:10.1016/j.ica.2008.11.023
(2009)Doi:10.1016/j.jorganchem.2009.02.005
(2009)Doi:10.1007/BF00958361
(1987)Doi:10.1021/jo00256a061
(1988)Doi:10.1139/V09-031
(2009)Doi:10.1016/S0022-328X(00)99821-8
(1987)