GENERAL ASYMMETRIC SYNTHESIS OF BENZOMORPHANS AND MORPHINANS VIA ENANTIOSELECTIVE HYDROGENATION

DOI: 10.1016/S0040-4039(00)96636-X

Source and publish data:

Tetrahedron Letters p. 4829 - 4832 (1987)

Update date:2022-08-04

Topics:

Authors:

Kitamura, M.

Hsiao, Yi

Noyori, R.

Takaya, H.

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Article abstract of DOI:10.1016/S0040-4039(00)96636-X

A variety of optically active benzomorphans including metazocine and pentazocine as well as dextromethorphan, a morphinan, are obtainable by using the BINAP-ruthenium(II) catalyzed enantioselective hydrogenation as key operation.

Full text of DOI:10.1016/S0040-4039(00)96636-X

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