Journal of Medicinal Chemistry p. 1823 - 1827 (1990)
Update date:2022-08-05
Topics: Synthesis Derivatives Chemical Compounds Experimental Piperazinyl Aryloxy Synthesis reaction
Walsh, David A.
Chen, Ying-Ho
Green, Jerry B.
Nolan, Joseph C.
Yanni, John M.
A series of 1-(aryloxy)-4-(4-arylpiperazinyl)-2-butanol derivatives were prepared and evaluated for antiallergy activity in the passive foot anaphylaxis (PFA) assay in rats.Twenty-seven derivatives had activity equal to or greater than the parent, α-(phen
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