Tetrahedron p. 3391 - 3398 (1988)
Update date:2022-07-31
Topics:
Hinkle, Jeffery S.
Lever, O. William
A method for the synthesis of isoquinolines functionalized with differentiated nitrogen substituents at positions 3 and 4 is described.The method involves tosylation of a 3-hydroxy-4-nitroisoquinoline and subsequent tosylate displacement by amine nucleoph
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