Diastereofacial Control in the Reaction of Chiral α-Amino Ketones with Several Organometallics

Article abstract of DOI:10.1246/cl.1988.59

The addition reaction of organometallics to chiral α-amino ketones, prepared from α-halo ketones and (S)-2-methoxymethylpyrrolidine as a chiral auxiliary, gave different diastereomers of chiral amino alcohols depending on the difference of coordination ab