
Tetrahedron p. 3149 - 3158 (1988)
Update date:2022-08-04
Topics:
Pereira, David E.
Petric, Andrej
Leonard, Nelson J.
The fluorescent 2,9-dichloro<2",3":1',2'>imidazo<4',5' :4,5>imidazo<1,2-b>pyridazine (2a) and the unsubstituted "parent" 2b have been synthesized.The chloro groups of 2a were found to be easily displaced by a variety of nucleophiles to provide the 2,9-disubstituted compounds 7-12.A single crystal X-ray structure determination of the 2,9-dimethoxy-substituted compound 7 revealed the existence of two crystallographically independent structures in the unit cell.It has been demonstrated that 2b can form a 2:1 complex with cobalt(II).
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