Synthesis and antimycobacterial activity of 5-formylaminopyrimidines; analogs of antibacterial purines

DOI: 10.1016/j.bmcl.2009.04.082

Source and publish data:

Bioorganic and Medicinal Chemistry Letters p. 3297 - 3299 (2009)

Update date:2022-07-29

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Authors:

Braendvang, Morten

Charnock, Colin

Gundersen, Lise-Lotte

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Article abstract of DOI:10.1016/j.bmcl.2009.04.082

Pyrimidine analogs of antimycobacterial purines have been synthesized and their biological activities evaluated. Several 5-formamidopyrimidines exhibited profound activity against Mycobacterium tuberculosis in vitro (IC₉₀ ≤ 1.5 μg/mL), and they

Full text of DOI:10.1016/j.bmcl.2009.04.082

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