Synthesis and antibacterial activity of novel 4-pyrrolidinylthio carbapenems - I. 2-alkoxymethyl derivatives

DOI: 10.1016/S0968-0896(97)00142-9

Source and publish data:

Bioorganic and Medicinal Chemistry p. 2069 - 2087 (1997)

Update date:2022-08-05

Topics: Synthesis Antibacterial activity

Authors:

Azami, Hidenori

Tsutsumi, Hideo

Matsuda, Keiji

Barrett, David

Hattori, Kouji

Nakajima, Takashi

Kuroda, Satoru

Kamimura, Toshiaki

Murata, Masayoshi

Read Full Text PDF DownLoad Join now for total 90,000,000 free articles

Article abstract of DOI:10.1016/S0968-0896(97)00142-9

The synthesis and in vitro antibacterial activity of a novel series of 2-alkoxymethyl-4-pyrrolidinylthio-1β-methyl carbapenems are described. As a result of these studies, we discovered that FR27743 (19j) containing a novel 2-fluoroethoxymethyl substituen

Full text of DOI:10.1016/S0968-0896(97)00142-9

Products guided by the article

Product name:(2S,4R)-1-benzyloxycarbonyl-2-(ethoxycarbonylmethyl)oxymethyl-4-methanesulfonyloxypyrrolidine

Cas No:117811-88-8

R&D Labs maybe for 117811-88-8

Tocopharm Co., Ltd.

Contact:+86-021-6989-5597

Address:No.80 Yichuan Rd., Putuo District,Shanghai,P.R.China
Chongqing Yawei Fine Chemical Co.,Ltd

Contact:0086-23-62849407

Address:Ziyou village, Nanquan town, Banan district, Chongqing China
Henan Harvest Chem Co., Ltd

Contact:+86-371-86058576

Address:NO.32, Jingsan Road, Zhengzhou, China
QINGDAO ON-BILLION INDUSTRAIL CO.,LTD

website:http://www.obn.com.cn

Contact:+86-15005320811 +86-532-80681989

Address:F35 Parkson Mansion No.44-60 Zhongshan Rd.
jiangsu hualin chemical co.,ltd.

Contact:86-25-87787402

Address:jaingsu,china

Relevant to this article

Intramolecular electron arrangement with a rotative trigger

Doi:10.1021/ja906684g
(2009)
First total syntheses of (+)-7-deoxynogarol and (+)-7-con-O-methylnogarol

Doi:10.1016/S0040-4039(00)80211-7
(1988)
Asymmetric total synthesis of reported structure of eudistomidin B, an indole alkaloid isolated from a marine tunicate

Doi:10.1016/j.tetlet.2009.05.069
(2009)
Radical Induced Regio- and Stereoselective Ring-Opening of gem-Difluorocyclopropanes. Synthesis of the (E)-Difluoroallylic System

Doi:10.1246/cl.1988.1407
(1988)
Reductive Addition of Polyhalomethanes and Their Related Compounds to Aldehydes and 1,2-Elimination of the Coupling Products in a Pb/Al Bimetal Redox System

Doi:10.1021/jo00263a035
(1989)
Stereoselective synthesis of (1-alkoxyalkyl) alpha- and beta-D-glucopyranosiduronates (acetal-glucopyranosiduronates): a new approach to specific cytostatics for the treatment of cancer.

Doi:10.1016/0008-6215(88)80082-X
(1988)

Article Doi