Synthesis and antibacterial activity of novel 4-pyrrolidinylthio carbapenems - I. 2-alkoxymethyl derivatives

DOI: 10.1016/S0968-0896(97)00142-9

Source and publish data:

Bioorganic and Medicinal Chemistry p. 2069 - 2087 (1997)

Update date:2022-08-05

Topics: Synthesis Antibacterial activity

Authors:

Azami, Hidenori

Tsutsumi, Hideo

Matsuda, Keiji

Barrett, David

Hattori, Kouji

Nakajima, Takashi

Kuroda, Satoru

Kamimura, Toshiaki

Murata, Masayoshi

Read Full Text PDF DownLoad Join now for total 90,000,000 free articles

Article abstract of DOI:10.1016/S0968-0896(97)00142-9

The synthesis and in vitro antibacterial activity of a novel series of 2-alkoxymethyl-4-pyrrolidinylthio-1β-methyl carbapenems are described. As a result of these studies, we discovered that FR27743 (19j) containing a novel 2-fluoroethoxymethyl substituen

Full text of DOI:10.1016/S0968-0896(97)00142-9

Products guided by the article

Product name:(2S,4R)-1-benzyloxycarbonyl-2-(ethoxycarbonylmethyl)oxymethyl-4-methanesulfonyloxypyrrolidine

Cas No:117811-88-8

R&D Labs maybe for 117811-88-8

Quhua Zhongxing Refrigeration Technology Co.,Ltd.

Contact:+86-5708886618

Address:318 Bulding 2, No.866 Quhua Rd.,Kecheng District
HENAN NEW BLUE CHEMICAL CO.,LTD

website:http://www.newbluechem.com

Contact:86-371-55170693/55170694

Address:Zhengzhou International Trade New Territory,Jinshui District,Zhengzhou ,China
Shenzhen Sunrising Industry Co., ltd.

Contact:+86 755 86571158 / 86571159 / 86571160

Address:2108 ZHENYE INT. BUSINESS CENTER,NO.3101-90 QIANHAI RD, NANSHAN,SHENZHEN, CHINA
Chemvon Biotechnology Co. Ltd.

website:http://www.chemvon.com

Contact:86-21-58550039;86-21-31268550-8004

Address:Suite B-10#, 6999 Chuansha Road, Pudong District, Shanghai 201202, China
Guarson Chemical Co., Ltd.

website:http://www.guarson.com

Contact:+86-523-88059600,+86-13805268803

Address:Room B1006,Yafang Building,Jiangyan Avenue,Jiangyan District, Taizhou City,Jiangsu,China

Relevant to this article

Intramolecular electron arrangement with a rotative trigger

Doi:10.1021/ja906684g
(2009)
First total syntheses of (+)-7-deoxynogarol and (+)-7-con-O-methylnogarol

Doi:10.1016/S0040-4039(00)80211-7
(1988)
Asymmetric total synthesis of reported structure of eudistomidin B, an indole alkaloid isolated from a marine tunicate

Doi:10.1016/j.tetlet.2009.05.069
(2009)
Radical Induced Regio- and Stereoselective Ring-Opening of gem-Difluorocyclopropanes. Synthesis of the (E)-Difluoroallylic System

Doi:10.1246/cl.1988.1407
(1988)
Reductive Addition of Polyhalomethanes and Their Related Compounds to Aldehydes and 1,2-Elimination of the Coupling Products in a Pb/Al Bimetal Redox System

Doi:10.1021/jo00263a035
(1989)
Stereoselective synthesis of (1-alkoxyalkyl) alpha- and beta-D-glucopyranosiduronates (acetal-glucopyranosiduronates): a new approach to specific cytostatics for the treatment of cancer.

Doi:10.1016/0008-6215(88)80082-X
(1988)

Article Doi