Studies on bioactive compounds. 13. Synthesis and lack of growth-inhibitory properties of cyclohexane-1,2,3-triol 1,2-diesters, which resemble ring C of the phorbol ester molecule

Article abstract of DOI:10.1021/jm00122a023

It has been suggested that ring C of biologically active phorbol esters is an essential structural feature of the pharmacophore which confers activity on these compounds. In this study the hypothesis has been tested that compounds which resemble ring C of