REACTION OF 2H-1-BENZOPYRANS WITH ORGANOMETALLIC REAGENTS. SYNTHESIS OF 4-(α,γ-DIALKYL-β-4-METHOXYPHENYLALLYL)RESORCINS

Article abstract of DOI:10.3987/COM-87-4373

The stereoselective synthesis of E- and Z-4-(α,γ-dialkyl-β-4-methoxyphenylallyl)resorcins was accomplished by reaction of 2-alkyl-7-hydroxy-4'-methoxyisoflavenes with organoaluminum and organomagnesium reagents.This way leads to better yields than the reduction of 2,4-dialkyl-7-hydroxy-4'-methoxyisoflavenes.The influence of substituents at different positions on the reduction was studied on model 2H-1-benzopyrans.