Journal of the Chemical Society. Perkin transactions I p. 1173 - 1178 (1988)
Update date:2022-08-05
Topics:
Crabb, Trevor A.
Trethewey, Andrew N.
Takeuchi, Yoshito
The position of conformational equilibria (CDCl3 solution; 298 K) of perhydrothiazolo<3,4-a>pyridine and the corresponding 6-ethyl-substituted derivatives have been determined by (1)H and (13)C n.m.r. spectroscopy.The reported synthesis of the 1-methylperhydrothiazolo<3,4-a>pyridines via 1-bromo-1-(2-piperidyl)ethane hydrobromide gave in addition the isomeric 9-methylperhydro-3,8-methano-1,3-thiazocines.Contrary to an earlier report trans-(1H,8aH)-1-methylperhydrothiazolo<3,4-a>pyridine was found to adopt an 87percent trans-fused <*> 13percent cis-fused conformational equilibrium (CDCl3; 193 K).
View MoreNanJing KaiHeng Chemical CO., LTD.
Contact:+86-25-85768391
Address:RM.1704, D, WANDA PLAZA, NO.110, MIDDLE JIANGDONG ROAD, NANJING, CHINA
Shuanghe Bio-Technology Limited(expird)
Contact:+86-571-61710758,18968016640
Address:Jinqiao north road 916# Fuyang
Suzhou Lixin Pharmaceutical Co., Ltd.
Contact:86-512-88169812
Address:21 Tangxi Road, Suzhou New District, Suzhou 215151
Changzhou Litong Chemical Co., Ltd.
website:http://www.litonchem.com/
Contact:+86-519-86301238
Address:Laoba Rd, Hutang town Changzhou Jiangsu
Contact:+86-518-81061113
Address:No. 8 Lingzhou Road, Lianyungang, Jiangsu, China
Doi:10.1016/0040-4039(88)85044-5
(1988)Doi:10.1021/ol901236s
(2009)Doi:10.1007/s11172-009-0180-6
(2009)Doi:10.1016/j.tet.2008.09.003
(2008)Doi:10.1016/j.tetlet.2008.09.122
(2008)Doi:10.1021/jo802345f
(2009)
