Structure-Activity Studies of Trichothecenes: Cytotoxicity of Analogues and Reaction Products Derived from T-2 Toxine and Neosolaniol

DOI: 10.1021/jm00123a008

Source and publish data:

Journal of Medicinal Chemistry p. 555 - 562 (1989)

Update date:2022-08-04

Topics:

Authors:

Anderson, D. W.

Black, R. M.

Lee, C. G.

Pottage, C.

Rickard, R. L.

et al. et al.

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Article abstract of DOI:10.1021/jm00123a008

Forty-two analogues and reaction products derived from T-2 toxin or neosolaniol were assayed for their cytotoxicity to cultured mouse lymphoma cells.Structure-activity relationships confirmed the stereospecific nature of the cytotoxic action of T-2.Cytoto

Full text of DOI:10.1021/jm00123a008

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