
Tetrahedron Letters p. 1431 - 1434 (1988)
Update date:2022-08-04
Topics:
Alexeev, S. G.
Charushin, V. N.
Chupakhin, O. N.
Alexandrov, G. G.
The reaction of 1,2,4-triazinium salts with amides of acetoacetic acid yielding 1,4,4a,5,7,7a-hexahydro-6H-pyrrolo<3,2-e>-1,2,4-triazin-6-ones exemplifies the first direct annelation to the 1,2,4-triazine ring based on the diaddition of bifunctional nucleophiles at C-5 and C-6.
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()Doi:10.1039/JR9330001547
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