Journal of Medicinal Chemistry p. 1935 - 1943 (1991)
Update date:2022-08-02
Topics:
Repine, Joseph
Himmelsbach, Richard J.
Hodges, John C.
Kaltenbronn, James S.
Sircar, Ila
et al.
A series of renin inhibitors containing ester side chains at the P2 subsite are potent inhibitors of primate renin.Derivatives containing the diol isostere (ACDMH) at P1-P'1 were the most potent inhibitors.Moderate selectivity for re
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