Journal of Organic Chemistry p. 10600 - 10616 (2016)
Update date:2022-08-15
Topics:
Nagasaki, Masahiro
Manabe, Yoshiyuki
Minamoto, Naoya
Tanaka, Katsunori
Silipo, Alba
Molinaro, Antonio
Fukase, Koichi
A chemical synthesis of a core fucose containing N-glycan was achieved. Asparagine was introduced at an early stage of the synthesis, and the sugar chain was convergently elongated. As for the fragment synthesis, we reinvestigated α-sialylation, β-mannosy
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