Characterization of a Product Derived from the 1-Methyl-4-phenyl-2,3-dihydropyridinium Ion, a Metabolite of the Nigrostriatal Toxin 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine

DOI: 10.1021/jo00266a011

Source and publish data:

Journal of Organic Chemistry p. 1052 - 1055 (1989)

Update date:2022-07-31

Topics:

Authors:

Leung, Louis

Ottoboni, Susanne

Oppenheimer, Norman

Castagnoli, Neal

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Article abstract of DOI:10.1021/jo00266a011

When incubated in aqueous pH 7.4 buffer, 1-methyl-4-phenyl-2,3-dihydropyridinium (MPDP⁺) perchlorate is transformed to a product (C23H23N) by a pathway that involves a net two-electron reductive dimerization reaction combined with a deamination

Full text of DOI:10.1021/jo00266a011

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