Tetrahedron Asymmetry p. 663 - 668 (2013)
Update date:2022-08-04
Topics:
Ramanujam, Rajendran
Ganjihal, Savita
Kalyanam, Nagabushanam
Majeed, Muhammed
The synthesis of chemically and enantiomerically pure (S)-3-amino tetrahydrofuran hydrochloride starting from the natural amino acids, l-aspartic acid or l-methionine is described. The process involves no chromatography and can be easily carried out on a large scale. The enantiopurity of the final product was established by NMR and chiral HPLC methods.
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