Asymmetric synthesis and σ receptor affinity of enantiomerically pure 1,4-disubstituted tetrahydro-1H-3-benzazepines

DOI: 10.1016/j.tetasy.2009.05.017

Source and publish data:

Tetrahedron Asymmetry p. 1383 - 1392 (2009)

Update date:2022-07-30

Topics:

Authors:

Husain, Syed Masood

Heim, Marie Theres

Schepmann, Dirk

Wuensch, Bernhard

Read Full Text PDF DownLoad Join now for total 90,000,000 free articles

Article abstract of DOI:10.1016/j.tetasy.2009.05.017

A very short (three steps) asymmetric synthesis of enantiomerically pure 1,4-disubstituted tetrahydro-1H-3-benzazepines 14 has been elaborated upon, starting from the trans- and cis-configured 11a-substituted 3-phenyl-2,3,11,11a-tetrahydro[1,3]oxazolo[2,3

Full text of DOI:10.1016/j.tetasy.2009.05.017

Products guided by the article

Product name:(3R,6S,11aR)-6-benzyl-11a-butyl-3-phenyl-2,3,11,11a-tetrahydro[1,3]oxazolo [2,3-b]-[3]-benzazepin-5(6H)-one

Cas No:1186339-77-4

R&D Labs maybe for 1186339-77-4

Hangzhou Sartort Biopharma Co., Ltd

website:http://www.sartort.com

Contact:86-571-87039693

Address:No. 57, Tech Park Road, Hangzhou, Zhejiang, China
Kono Chem Co.,Ltd

website:http://www.konochem.com

Contact:86-29-86107037-8015

Address:No.11 Daqing Road,Lianhu District,Xi’an 710082,China
CHEM PLUS

Contact:0027-717-456976

Address:2ND FLOOR, 325 VAUSE ROAD, OVERPORT, 4001, SOUTH AFRICA
Zhejiang Haizhou Pharmaceutical Co., Ltd.

website:https://www.haizhoupharma.com/

Contact:+86-576-88221016

Address:No. 19, Donghai 5th Avenue, Yanhai Industrial Zone, Linhai, Zhejiang, China
Anhui Jiatiansen Agrochemical Co.,Ltd

Contact:15366811918

Address:chemical industrial park,xiangyu town,dongzhi county,anhui,china

Relevant to this article

Pyrrolidine analogues of lobelane: Relationship of affinity for the dihydrotetrabenazine binding site with function of the vesicular monoamine transporter 2 (VMAT2)

Doi:10.1021/jm900770h
(2009)
Isolation of Cp*Co^III–Alkenyl Intermediate in Efficient Cobalt-Catalyzed C?H Alkenylation with Alkynes

Doi:10.1002/chem.201705183
(2018)
Stereoselective total synthesis of dodoneine

Doi:10.1002/hlca.200900478
(2010)
Hydrogen bonding interaction of CpCo(Dithiolene) complex with monocyclic 2-pyridonyl substituent and unexpected formation of dithiolene-fused tricyclic pyridone derivative

Doi:10.1016/j.jorganchem.2009.04.022
(2009)
KI-catalyzed aminobromination of olefins with TsNH₂-NBS combination

Doi:10.1039/b904789a
(2009)
Water-soluble phosphate prodrugs of pleuromutilin analogues with potent in vivo antibacterial activity against Gram-positive pathogens

Doi:10.1016/j.bmcl.2009.07.115
(2009)

Article Doi