Cardiotonic agents 4. Dimaprit analoues as potential cardiovascular selective H2-agonists

DOI: 10.1016/0223-5234(88)90013-X

Source and publish data:

European Journal of Medicinal Chemistry p. 295 - 300 (1988)

Update date:2022-08-03

Topics: Selective Potential Cardiotonic agents

Authors:

Owens, Albert H.

Goehring, R. Richard

Lampe, John W.

Erhardt, Paul W.

Lumma, William C.

Wiggins, Jay

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Article abstract of DOI:10.1016/0223-5234(88)90013-X

Several derivatives of dimaprit including carbon chain substitution, nitrogen substitution and isothiourea replacements were prepared and tested for inotropic activity in guinea pig papillary muscle preparations.Two derivatives showed moderate positive in

Full text of DOI:10.1016/0223-5234(88)90013-X

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