C-GLYCOSYLATION OF SUBSTITUTED HETEROCYCLES UNDER FRIEDEL-CRAFTS CONDITIONS (I): A TWO-STEP SYNTHESIS OF THE THIENOPYRIMIDINE c-NUCLEOSIDE ANALOG OF INOSINE.

Article abstract of DOI:10.1016/0040-4039(88)85286-9

Direct stannic chloride catalyzed C-glycosylation of N-formyl-4-amino-3-carboalkoxy thiophenes with 1-O-acetyl-O-benzoyl-β-D-ribofuranose, followed by annelation of a fused pyrimidone ring upon treatment with ammonia, constitutes a short approach to the synthesis of a new C-nucleoside inosine analog.