Improved condensation of 2-pyridyllithium intermediates with aldehydes: Application for the Synthesis of 2 (polyhydroxyalkyl)pyridines

DOI: 10.2174/157017809787003214

Source and publish data:

Letters in Organic Chemistry p. 50 - 56 (2009)

Update date:2022-08-04

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Authors:

Comoy, Corinne

Petrignet, Julien

Banaszak, Estelle

Chartoire, Anthony

Fort, Yves

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Article abstract of DOI:10.2174/157017809787003214

The scope and the limitations of 3-chloro-2-pyridinyl lithium condensation to aldehydes were envisioned depending on metallation conditions or condensation time and temperatures. The procedure was applied to various aromatic, aliphatic or functionalized a

Full text of DOI:10.2174/157017809787003214

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