Bioorganic and Medicinal Chemistry Letters p. 5086 - 5090 (2009)
Update date:2022-08-05
Topics:
Lee, Jeong Tae
Chen, David Y.
Yang, Zhimou
Ramos, Alexander D.
Hsieh, James J.-D.
Bogyo, Matthew
Taspase1 is a threonine protease responsible for cleaving MLL (Mixed-Lineage Leukemia) to achieve proper HOX gene expression. Subsequent studies identified additional Taspase1 substrates including Transcription Factor IIA (TFIIA) and Drosophila HCF. Taspa
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